Dr. Jose Maciel Larios completed a postdoctoral fellowship in a breast oncology/pharmacology lab at the University of Michigan. During his fellowship, Dr. Larios investigated molecular mechanisms of endocrine resistance in hormone receptor-positive breast cancer. He recapitulated newly published mutations in the estrogen receptor gene using breast cancer cell lines as pre-clinical models. Additionally, Dr. Larios also examined mechanisms of resistance to CDK4/6 inhibitors. He is a member of the American Society of Hematology and the American Society of Clinical Oncology. As a transplant hematologist, he would like to explore the role of the bone marrow microenvironment in leukemia progression.
Research and Clinical Interests: