The Barbara Ann Karmanos Cancer Institute welcomes José Larios, M.D., transplant hematologist. Dr. Larios is a member of the Bone Marrow and Stem Cell Transplant and Hematology Oncology Multidisciplinary Teams at Karmanos. He specializes in treating leukemia and lymphoma blood cancers, including Hodgkin and non-Hodgkin lymphomas. He began seeing patients at the Karmanos Cancer Center in Detroit in August 2024.
"Karmanos Cancer Institute is an NCI (National Cancer Institute)-Designated Comprehensive Cancer Center known for its expertise in treating solid and hematologic tumors,” said Dr. Larios. “During my fellowship training, I was privileged to work with the incredible transplant and hematology teams, under the guidance and mentorship of Dr. Uberti in stem cell transplant and Dr. Yang in malignant hematology. I am now honored to be a part of the hematology and transplant team at the Barbara Ann Karmanos Cancer Institute."
Dr. Larios has research and clinical interests in the role of bone marrow microenvironment in leukemia progression. This includes bone marrow signaling in acute leukemias, stem cell transplantation, and cellular therapy. He completed his postdoctoral fellowship in a breast oncology and pharmacology lab at the University of Michigan and investigated molecular mechanisms of endocrine resistance in hormone receptor-positive breast cancer. He recapitulated newly published mutations in the estrogen receptor gene using breast cancer cell lines as pre-clinical models. Additionally, Dr. Larios also examined mechanisms of resistance to CDK4/6 inhibitors.
“With Karmanos being an NCI-Designated Comprehensive Cancer Center, in partnership with Wayne State University, Dr. Larios’ research and interests will lead to significant discovery in the way we currently treat leukemias and lymphomas with stem cell transplantation,” explained George Yoo, M.D., FACS, Chief Medical Officer at Karmanos Cancer Hospital. “Having physicians that push the standard of care needle forward is just what we need in the fight against cancer, to help with future treatments that cure cancers and lead to a better quality of life after treatment.”
In addition to his postdoctoral fellowship work, Dr. Larios completed an internal medicine residency at Ascension Providence Hospital in Southfield and received his medical degree at Ross University School of Medicine, which was in Dominica at that time. He is board-certified by the American Board of Internal Medicine, where he is also a diplomate in Internal Medicine. He is a member of the American Society of Hematology, the American Society of Clinical Oncology, and the American Medical Association. He serves on the editorial board for the European Journal of Neurology and has co-authored multiple peer-reviewed published studies.
View Dr. Lario’s physician profile here. To request an appointment, visit karmanos.org or call 1-800-KARMANOS.